Thursday, May 10, 2012

First study investigating possible link between sunscreen ingredient and endometriosis

First study investigating possible link between sunscreen ingredient and endometriosis [ Back to EurekAlert! ] Public release date: 9-May-2012
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Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Scientists are reporting a possible link between the use of sunscreen containing a certain ingredient that mimics the effects of the female sex hormone estrogen and an increased risk of being diagnosed with endometriosis, a painful condition in which uterine tissue grows outside the uterus. They describe the report, published in ACS' journal Environmental Science & Technology, as the first to examine whether such a connection may exist.

Kurunthachalam Kannan and colleagues explain that some sunscreens and other personal care products contain benzophenone (BP)-type ingredients that are very effective in blocking potentially harmful ultraviolet rays from the sun. Small amounts of BPs can pass through the skin and be absorbed into the blood, where they mimic the effects of estrogen. Endometriosis, which affects up to 1-in-10 women of reproductive age, needs estrogen to develop. Despite those facts, scientists until now had not checked for a connection between the use of BP sunscreens and the likelihood of being diagnosed with endometriosis.

To fill that knowledge gap, the scientists analyzed BP levels in the urine of 625 women who underwent surgery for endometriosis. They found that high levels of one BP called 2,4OH-BP were associated with an increased risk of an endometriosis diagnosis. Women tended to have higher levels of BPs during the summer months and if they lived in sunny California, further suggesting a link with sunscreens. "Our results invite the speculation that exposure to elevated 2,4OH-BP levels may be associated with endometriosis," say the researchers.

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The researchers acknowledge funding from the Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society contact newsroom@acs.org.



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First study investigating possible link between sunscreen ingredient and endometriosis [ Back to EurekAlert! ] Public release date: 9-May-2012
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Scientists are reporting a possible link between the use of sunscreen containing a certain ingredient that mimics the effects of the female sex hormone estrogen and an increased risk of being diagnosed with endometriosis, a painful condition in which uterine tissue grows outside the uterus. They describe the report, published in ACS' journal Environmental Science & Technology, as the first to examine whether such a connection may exist.

Kurunthachalam Kannan and colleagues explain that some sunscreens and other personal care products contain benzophenone (BP)-type ingredients that are very effective in blocking potentially harmful ultraviolet rays from the sun. Small amounts of BPs can pass through the skin and be absorbed into the blood, where they mimic the effects of estrogen. Endometriosis, which affects up to 1-in-10 women of reproductive age, needs estrogen to develop. Despite those facts, scientists until now had not checked for a connection between the use of BP sunscreens and the likelihood of being diagnosed with endometriosis.

To fill that knowledge gap, the scientists analyzed BP levels in the urine of 625 women who underwent surgery for endometriosis. They found that high levels of one BP called 2,4OH-BP were associated with an increased risk of an endometriosis diagnosis. Women tended to have higher levels of BPs during the summer months and if they lived in sunny California, further suggesting a link with sunscreens. "Our results invite the speculation that exposure to elevated 2,4OH-BP levels may be associated with endometriosis," say the researchers.

###

The researchers acknowledge funding from the Intramural Research Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health.

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society contact newsroom@acs.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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